The global downstream processing market size is expected to reach USD 65.66 Billion by 2028 according to a new study by Polaris Market Research. The report “Downstream Processing Market Share, Size, Trends, Industry Analysis Report, By Technique (Cell Disruption, Solid-liquid Separation, Concentration, Purification by Chromatography, Formulation); By Product; By Application; By Regions; Segment Forecast, 2021 – 2028” gives a detailed insight into current market dynamics and provides analysis on future market growth.
Downstream processing is a form of process that involves purification and the recovery of biosynthetic products, especially pharmaceuticals derived from natural sources. It is divided into five stages: solid-liquid separation, intracellular substance release, concentration, and purification and formulation using chromatography. Flocculation, centrifugation flotation, and filtration are examples of solid-liquid separation methods.
Rising demand for biological products, increasing implementation of biotech practices in the agricultural, pharmaceutical, and bio-services industries, the developments in the field of gene therapy and genetic engineering, and increasing adoption of single-umbrella solutions are all contributing to market growth for downstream processing.
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The bandwidth requirements for biologic drug production have shifted in recent years, with the market for high-volume products giving way to the development of small-volume, high-potency products. This opens lucrative opportunities for single-use downstream processing technology.
Evolutionary developments in single-use system for producing small amount, very effective drugs are anticipated, given that small-scale, single-use systems are already widely used for process creation and downstream processing. Innovative film chemistries, closed systems, clinical-scale single-use device optimization, and smart sensors are only a few of the notable innovations in the field.
Market participants such as 3M Company, Danaher Corporation, Ashai Kasei, Corning Corporation, Lonza Group Ltd, Boehringer Ingelheim International GmbH, Dover Corporation, Eppendorf AG, Ferner PLC, Merck KGaA, GE Healthcare, Sartorius Stedim Biotech S.A, Thermo Fisher Scientific Inc., and Repligen are some of the leading players operating in the market for downstream processing.
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The market is expected to grow as the number of downstream processing applications for biopharmaceutical manufacturing grows. This has resulted in a rise in strategic deals and business growth for downstream processing. Evozyne, LLC, for example, collaborated with a leading rare disorders drug manufacturer in February 2021, to produce and market novel immune modulation biopharmaceuticals.
Polaris Market Research has segmented the Downstream Processing market report based on product, technique, and application, and region:
Downstream Processing, Product Outlook (Revenue – USD Billion, 2016 – 2028)
- Chromatography Systems
- Filters
- Evaporators
- Centrifuges
- Dryers
- Others
Downstream Processing, Technique Outlook (Revenue – USD Billion, 2016 – 2028)
- Cell Disruption
- Solid-liquid separation
- Filtration
- Centrifugation
- Concentration
- Evaporation
- Membrane filtration
- Purification by Chromatography
- Formulation
Downstream Processing, Application Outlook (Revenue – USD Billion, 2016 – 2028)
- Antibiotic Production
- Hormone Production
- Antibodies Production
- Enzyme Production
- Vaccine Production
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